Design

Department of Pharmaceutical Chemistry Page 15 small molecules that are complementary in shape and charge to the biomolecular target with which they interact and therefore will

In the Hypogen studies 10 hypotheses were generated using the most diverse 24 molecules from the training set (Fig.5d) and validated using 201 test molecules.

The antibacterial activities of synthesized compounds were screened in the concentration of 0.1mg in dimethyl sulphoxide against the above mentioned bacteria in the Muller

Department of Pharmaceutical Chemistry Page 84 deoxyuridine Monophosphate Analogues As Inhibitors of Flavin-Dependent Thymidylate Synthase in Mycobacterium tuberculosis., J. Paola

The drug delivery system is a Capsule consisting of Lafutidine blend, Domperidone Immediate release tablets and Domperidone sustain release tablets.. The Capsule dosage form is the

Use of agar as base of rapidly disintegrating oral tablets. Mouth dissolving tablets: A review.. Fast disintegrating tablets of atenolol by dry granulation method. Added

Screening for In vitro Anti tumor activity against human cervical cancer cell line (HeLa) by MTT assay method.. Screening for the Antimicrobial activity against various microorganisms

In the drug reservoir compartment, the drug solids are either dispersed homogenously in a solid polymer matrix (e.g. Polyisobutylene adhesive) or suspended in an

 Identification of the common Pharmacophore responsible for the inhibition of mmaa2 using hip-hop molecule of catalyst software 4.11 from accelrys.  Using scaffold hopping

JERAD SURESH, M.Pharm., Ph.D., M.B.A., Principal, Professor and Head, Department of Pharmaceutical chemistry, College of Pharmacy, Madras Medical College, Chennai-60003...

Department of Pharmaceutical Chemistry, MMC, Madurai. S.Mhan et al., synthesized some chloro, methoxy substituted chalcone derivatives and tested for anti microbial activity, 2012.

Freezing is generally the first step in a freeze-drying process, in which nearly 90% of the water is converted to ice crystals while all solutes in the formulation are

While until the 90s, the major issues were lead discovery and chemical synthesis of drug-like molecules, the emergence of combinatorial chemistry gene technology,

This is to certify that the dissertation work entitled “ DESIGN, FABRICATION AND CHARACTERIZATION OF THROMBOLYTIC ACTIVITY OF BAUHINIA RACEMOSA EXTRACT LOADED NANOEMULSION ” is a

Department of Pharmaceutics, Madras Medical College Page 114 The present work involves the design, development and in-vitro evaluation of Captopril floating pulsatile

Our work concludes that based on docking G-Score our synthesized molecules were effective in inhibiting the target enzyme Diaminopimelate decarboxyl ase (LysA)Score,

Page 18 Another important method for drug discovery is FBLD drug design, whereby the biological and physical properties of the target are studied, and a prediction is made on

(84) The small molecule called ligand usually interacts with the protein binding site.There are several possible mutual conformations in which binding may occur. These are