Design, synthesis and evaluation of thiazole based amides for their antitubercular and PknG inhibitory activity

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Supplementary Information

Design, synthesis and evaluation of thiazole based amides for their antitubercular and PknG inhibitory activity

Anindra Sharma

Department of Chemistry, A.P.S.M College, Barauni, Begusarai 851 112, India (A Constituent Unit of Lalit Narayan Mithila University, Darbhanga)

E-mail: anindrasharma2007@gmail.com

Received 22 June 2020; accepted (revised) 4 March 2021

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Content Page Figure S1. ¹H NMR spectrum of compound 1 S3

Figure S2.¹³C NMR spectrum of compound 1 S3 Figure S3. ¹H NMR spectrum of compound 2 S4 Figure S4.¹³C NMR spectrum of compound 2 S4 Figure S5. ¹H NMR spectrum of compound 3 S5 Figure S6.¹³C NMR spectrum of compound 3 S5 Figure S7. ¹H NMR spectrum of compound 4 S6 Figure S8.¹³C NMR spectrum of compound 4 S6 Figure S9. ¹H NMR spectrum of compound 5 S7 Figure S10.¹³C NMR spectrum of compound 5 S7 Figure S12.¹³C NMR spectrum of compound 6 S8 Figure S13. ¹H NMR spectrum of compound 7 S8 Figure S14.¹³C NMR spectrum of compound 7 S9 Figure S15. ¹H NMR spectrum of compound 8 S9 Figure S16.¹³C NMR spectrum of compound 8 S10 Figure S17. ¹H NMR spectrum of compound 9 S10 Figure S21. ¹H NMR spectrum of compound 11 S11

S3 Figure S1. ¹H NMR spectrum of compound 1

Figure S2. ¹³C NMR spectrum of compound 1

S4 Figure S3. ¹H NMR spectrum of compound 2

Figure S4. ¹³C NMR spectrum of compound 2

S5 Figure S5. ¹H NMR spectrum of compound 3

Figure S6. ¹H NMR spectrum of compound 3

S6 Figure S7. ¹H NMR spectrum of compound 4

Figure S8. ¹³C NMR spectrum of compound 4

S7 Figure S9. ¹³C NMR spectrum of compound 5

Figure S10. ¹³C NMR spectrum of compound 5

S8 Figure S11. ¹³C NMR spectrum of compound 6

Figure S12. ¹H NMR spectrum of compound 7

S9 Figure S13. ¹³C NMR spectrum of compound 7

Figure S14. ¹H NMR spectrum of compound 8

S10 Figure S15. ¹³C NMR spectrum of compound 8

Figure S16. ¹H NMR spectrum of compound 9

S11 Figure S17. ¹H NMR spectrum of compound 11